Abstract: A soil pot-culture experiment was carried out to study maize（Zea mays L.） and crabgrass（Digitaria sanguinalis (L．)Scop．） response to cadmium toxicity. The results showed that under the same level of Cd, contents sequence of Cd in the different organs of maize was root>stem>leaf>seed both intercropping and mono-cropping system. Contents sequence of Cd in the same organs of maize was 10mg>5mg>0mg under different levels of Cd. Compred with the control, crabgrass of intercropping accumulate more Cd than crabgrass of mono-cropping. Crabgrass accelerated the maize for uptake and accumulation of Cd and distrite them in roots of the maize in intercropping system. The initial test showed that crabgrass and maize promoted uptake and accumulation of Cd in intercropping system each other.