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Chinese Agricultural Science Bulletin ›› 2009, Vol. 25 ›› Issue (16): 21-24.

• 畜牧兽医科学 • Previous Articles     Next Articles

Study on in Vitro Antifungal Activity of Dictamnine against Candida albicans

Liang Xiaoying, Guo Na,, Wang Lisha, Jin Jing, Shi Jianping, Lu Huijun, Deng Xuming, Yu Lu   

  • Received:2009-06-23 Revised:2009-07-03 Online:2009-08-20 Published:2009-08-20

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Abstract: Candida albicans (C. albicans) and other fungi an important human and veterinary pathogens. The minimal inhibitory concentration (MIC) of dictamnine alone and in combination with fluconazole (FLC) against clinical 22 clinical Candida albicans were tested, and checkerboard assay was used to analyzed the ractional inhibitory concentration index (FICI) of the combination of dictamnine and FLC. The result showed that dictamnine had good antifungal activity alone and in combination with FLC against Candida albicans.