Abstract:

Abstract: Objective The therapeutic effect of the self-made organic iodine suppositories was observed to the rabbits endometritis pathological model.Methods Rabbit endometritis pathological model was copied by the way of perfusing pathogenic E. coli, staphylococcus, streptococcus, Salmonella, Bacillus cereus and other mixed bacilli to the uterine. Put the organic iodine suppository to the uterine in the 1st,3rd,5thdays drespectively, according to 0.01g/kg weight (in terms of effective iodine) for treatment, to observe the clinical symptoms, uterine shape, pathological changes of endometrium and serum SOD, MDA, GSH-Px and other biochemical parameters before and after treatment. Results In the 4thd,vulva swelling and vaginal congestion gradually subsided ,uterine secretions gradually reduced; cervical and horn of the uterine swell slightly, a small amount of clear secretions is inside the uterine; endometrial is more complete, epithelial cell structure is normal. In the4thd, serum SOD and GSH-Px in treatment group activity were significantly higher than that in pathological control group (P<0.05). While in the 6thd, serum SOD in treatment group activity was significantly higher than that in pathological control group (P<0.05),serum GSH-Px activity was very significantly higher than that in pathological control group (P <0.01),serum MDA contents was very significantly lower than that in pathological control group (P <0.01).Conclusion The organic iodine suppository may be effectively cure the rabbit endometritis.