Abstract: The objective of this study was to determine the effect of three controls nutrient management technology on growth, development and nitrogen uptake of rice. Two field experiments were conducted in early season and late season of 2009 at Baiyun experimental station, Guangdong Academy of Agricultural science, Guangzhou, china. Yueza 889, a two-line hybrid rice, was grown under two treatments, three controls nutrient management technology and farmers′fertilizer practice (FFP), and arranged in randomized complete block design experiments with four replicates. The results were as follows: (1) Compared with FFP, grain yield with three controls treatment was 6 %~8 % higher, while total nitrogen input was 10% lower. Panicles number, filled grain rate and 1000-grain weight were greater than FFP. (2) Total plant dry weight under three controls treatment was 3.8%~11.0% greater than that under FFP. Chlorophyll content of leaves (SPAD value) of three controls treatment was higher than that of FFP during panicle initiation and grain-filling stages. Little difference was found in leaf area index between three controls treatment and FFP. (3) Compared with FFP, maximum tiller number of three controls treatment was 5.9%~10.6% lower, but the productive tiller rate was 5.5%~11.8% higher. (4) Plants under three controls treatment absorbed less nitrogen than FFP before panicle initiation. But during panicle initiation and grain-filling stages, plants under three controls treatment absorbed much more nitrogen than FFP. Total N uptake and nitrogen use efficiency, i.e. recovery efficiency, agronomic efficiency and partial factor productivity, were higher for three controls treatment than for FFP.