Abstract: Experimental alteration of Eucalyptus grandis × E. tereticornis DH201-2 plantation totally 74.3 hm2 severely attacked by Leptocybe invasa Fisher & La Salle in Ningming and Longzhou of Guangxi was carried out from November 2008 to January 2010, results show that the replanted plantations are not attacked by Leptocybe invasa Fisher & La Salle, forests average height reach 4.0m and 3.5m, average diameter at breast height get to 3.9cm and 3.3cm respectively in two places 9 months after replanting, technologies utilized are proved to be effective, which are clearcutting of infected trees to kill the existing Leptocybe invasa Fisher & La Salle; digging up the stumps to stop supplying Leptocybe invasa Fisher & La Salle with host sprouting from the stumps; selection of replanted species of Eucalyptus urophylla × E. grandis DH32-29 with high resistance to Leptocybe invasa Fisher & La Salle; advanced silvicultural measures such as digging planting holes with digging machine, planting in favourable season, tending and fertilizing in time etc. to accelerate the forest growth. It also comes out that alteration of infected forest can recover the plantation of Eucalyptus grandis × E. urophylla GL9 nearby, which is not easily infectious to but affected by Leptocybe invasa Fisher & La Salle. Alteration of forest attacked by Leptocybe invasa Fisher & La Salle is pointed out to be an important measure for controlling Leptocybe invasa Fisher & La Salle in China currently.