The aim of this study is to investigate the effects of tillage practices on soil properties, aggregate stability and soil quality, providing references for improving soil fertility and yield in drip-irrigated maize fields in Xinjiang. A field positioning experiment was conducted in Areoletuohai Ranch, Bole City, Xinjiang from 2022-2023 with the maize variety ‘Jinli1702’ as the test material. Four tillage treatments were set up, including conventional tillage with plastic film (CT), conventional tillage without plastic film (BT), no-tillage (NT) and shallow tillage (ST). The changes in soil properties, aggregate fractions and maize yield were analyzed to evaluate the effects of tillage practices on soil quality and maize yield. The results showed that compared with CT, both NT and ST significantly increased >2 mm aggregate contents, mean weight diameter (MWD), geometric mean diameter (GMD), and R0.25 (P<0.05), indicating improved soil aggregate stability. Under the CT, soil temperature and moisture content were significantly higher than that in the NT and ST. Soil bulk density ranged from 1.35 to 1.70 g/cm3, with NT and ST showing significantly higher levels of available phosphorus, total nitrogen and organic carbon compared to CT. The soil quality index (SQI) in NT and ST increased by 19.82% and 15.29%, respectively, compared to CT. Maize yield under NT and ST was significantly higher than under CT and BT, reaching 20.67 t/hm2 and 19.84 t/hm2, respectively. But, there were no differences in ear grain number across four treatments, while the thousand-grain weight of NT was significantly higher than that of the others (P<0.05). Mantel analysis revealed significant positive correlations between yield and aggregate stability indices (MWD, GMD, D and R0.25), soil properties, and SQI. Structural equation modeling showed that tillage practices affected soil quality by altering soil aggregate stability and soil properties, thereby indirectly influencing maize yield. The results showed that the yield of NT and ST increased by 9.13 % and 4.75 % compared with conventional tillage in drip irrigation maize farmland in Xinjiang, which had a significant effect on soil structure stability, soil quality and maize yield.