尖孢镰刀菌SIX效应因子研究进展

doi:10.11924/j.issn.1000-6850.casb2024-0119

中国农学通报 ›› 2024, Vol. 40 ›› Issue (36): 132-139.doi: 10.11924/j.issn.1000-6850.casb2024-0119

尖孢镰刀菌SIX效应因子研究进展

陈益文¹(), 彭存智², 徐兵强²^,³()

¹ 华中农业大学园艺林学学院，武汉 430070
² 中国热带农业科学院热带生物技术研究所，海口 571101
³ 中国热带农业科学院三亚研究院，海南三亚 572025

收稿日期:2024-02-27 修回日期:2024-05-15 出版日期:2024-12-25 发布日期:2024-12-23
通讯作者:
徐兵强，男，1979年出生，江西宜春人，研究员，博士，研究方向：蛋白质组学。通信地址：571101 海南省海口市龙华区学院路，中国热带农业科学院热带生物技术研究所，E-mail：erger2002@163.com。
作者简介:
陈益文，男，1998年出生，海南澄迈人，硕士研究生，研究方向：植物病原真菌学。通信地址：571101 海南省海口市龙华区学院路，中国热带农业科学院热带生物技术研究所，E-mail：chenyiwenjack@foxmail.com。
基金资助:
海南省自然科学基金高层次人才项目“香蕉枯萎病分泌蛋白Six1和Six4/6在香蕉免疫反应中的作用机制研究”(320RC707); 中央级公益性科研院所基本科研业务费专项“热带重要病害（香蕉枯萎病）病程蛋白组草图绘制与应用”(1630052022010)

Research Progress on SIX Effectors of Fusarium oxysporum

CHEN Yiwen¹(), PENG Cunzhi², XU Bingqiang²^,³()

¹ College of Horticulture and Forestry, Huazhong Agricultural University, Wuhan 430070
² Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101
³ Sanya Research Institute, Chinese Academy of Tropical Agricultural Sciences, Sanya, Hainan 572025

Received:2024-02-27 Revised:2024-05-15 Published:2024-12-25 Online:2024-12-23

摘要/Abstract

摘要：

尖孢镰刀菌(Fusarium oxysporum，Fo)是导致农作物枯萎的土传性真菌病害，该病害严重制约了农业的可持续发展。效应因子是病原菌与农作物互作过程中的关键因子，对其作用机理解析可为病菌病害防治提供切实有效的策略。Fo在侵染农作物时，会在其维管束木质部分泌一种蛋白，称为SIX效应蛋白(Secreted In Xylem)。为了研究SIX效应因子在病原菌Fo与寄主植物间的作用方式，分析了SIX效应因子在Fo染色体组上的结构特点，归纳了SIX效应因子鉴别Fo不同的专化型和生理小种、影响Fo致病性以及影响寄主植物免疫反应等方面的功能特点，并指出SIX效应因子不仅对寄主植物有毒力作用，还能与植物发生非亲和互作来影响病原菌的入侵。本研究结果揭示了SIX效应因子在不同方面对植物的作用与影响，也为植物抗病分子机理研究和植物抗病品种选育提供了理论支持。

关键词: 尖孢镰刀菌, 致病性, 免疫反应, 枯萎病, 效应蛋白, SIX效应因子, 结构特点, 专化型和生理小种, 无毒因子

Abstract:

Fusarium oxysporum (Fo) is a soil-borne fungal disease that causes crop wilting, which is a serious constraint to the sustainable development of agriculture. Effectors are key factors in pathogen-plant interactions, and their mechanism of action can be analyzed to provide effective strategies for controlling plant diseases. When Fo infects crops, it secretes a protein in the xylem of vascular bundles, which is called Secreted In Xylem effector protein (SIX). In order to study the role of SIX effectors between Fo and plants, the structural characteristics of SIX on the Fo genome were analyzed. The functional attributes of SIX in identifying different formae speciales and physiological races of Fo, influencing the pathogenicity of Fo, and affecting the immune response of plants were summarized. It was pointed out that SIX had toxic effects on plants and could interact with plants in an incompatible manner to influence the invasion of pathogens. The results of this study reveal the effects of SIX on plants in different aspects and provide theoretical support for the study of the molecular mechanism of plant disease resistance and the selection and breeding of disease-resistant varieties.

Key words: Fusarium oxysporum, pathogenicity, immune response, wilting disease, effector proteins, SIX effectors, structural characteristics, formae speciales and physiological races, avirulence genes

陈益文, 彭存智, 徐兵强. 尖孢镰刀菌SIX效应因子研究进展[J]. 中国农学通报, 2024, 40(36): 132-139.

CHEN Yiwen, PENG Cunzhi, XU Bingqiang. Research Progress on SIX Effectors of Fusarium oxysporum[J]. Chinese Agricultural Science Bulletin, 2024, 40(36): 132-139.

图/表 3

参考文献 67

[1]	SRINIVAS C, NIRMALA D D, NARASIMHA M K, et al. Fusarium oxysporum f. sp. lycopersici causal agent of vascular wilt disease of tomato: biology to diversity- a review[J]. Saudi journal of biological sciences, 2019, 26(7):1315-1324.
[2]	裴月令, 曾凡云, 彭军, 等. 尖孢镰刀菌与寄主互作机理研究进展[J]. 热带生物学报, 2014, 5(1):92-100.
[3]	王泽华, 方香玲. 尖孢镰刀菌遗传多样性研究进展[J]. 中国草地学报, 2021, 43(5):106-114.
[4]	JONES J D G, DANGL J L. The plant immune system[J]. Nature, 2006, 444(7117):323-329.
[5]	NGOU B P M, DING P, JONES J D G. Thirty years of resistance: Zig-zag through the plant immune system[J]. Plant cell, 2022, 34(5):1447-1478.
[6]	REP M, VAN DER DOES H C, MEIJER M, et al. A small, cysteine-rich protein secreted by Fusarium oxysporum during colonization of xylem vessels is required for I-3-mediated resistance in tomato[J]. Molecular microbiology, 2004, 53(5):1373-1383.
[7]	SCHMIDT S M, HOUTERMAN P M, SCHREIVER I, et al. MITEs in the promoters of effector genes allow prediction of novel virulence genes in Fusarium oxysporum[J]. BMC genomics, 2013, 14(1):119.
[8]	SIMBAQUEBA J, RODRÍGUEZ E A, BURBANO-DAVID D, et al. Putative novel effector genes revealed by the genomic analysis of the phytopathogenic fungus Fusarium oxysporum f. sp. physali (Foph) that infects cape gooseberry plants[J]. Front in microbiology, 2021,11:593915.
[9]	LAURENCE M H, SUMMERELL B A, LIEW E C Y. Fusarium oxysporum f. sp. canariensis : evidence for horizontal gene transfer of putative pathogenicity genes[J]. Plant pathology, 2015, 64(5):1068-1075.
[10]	HUMAN M P, BERGER D K, CRAMPTON B G. Time-course rnaseq reveals Exserohilum turcicum effectors and pathogenicity determinants[J]. Frontiers in microbiology, 2020,11:360.
[11]	RAFIQI M, JELONEK L, DIOUF A M, et al. Profile of the in silico secretome of the palm dieback pathogen, Fusarium oxysporum f. sp. albedinis, a fungus that puts natural oases at risk[J]. Plos one, 2022, 17(5):e0260830.
[12]	MA L J, VAN DER DOES H C, BORKOVICH K A, et al. Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium[J]. Nature, 2010, 464(7287):367-373.
[13]	WILLIAMS A H, SHARMA M, THATCHER L F, et al. Comparative genomics and prediction of conditionally dispensable sequences in legume-infecting Fusarium oxysporum formae speciales facilitates identification of candidate effectors[J]. BMC genomics, 2016,17:191.
[14]	LI J, FOKKENS L, CONNEELY L J, et al. Partial pathogenicity chromosomes in Fusarium oxysporum are sufficient to cause disease and can be horizontally transferred[J]. Environmental microbiology, 2020, 22(12):4985-5004.
[15]	FESCHOTTE C, PRITHAM E J. DNA transposons and the evolution of eukaryotic genomes[J]. Annual review of genetics, 2007,41:331-368.
[16]	WICKER T, SABOT F, HUA-VAN A, et al. A unified classification system for eukaryotic transposable elements[J]. Nature reviews genetics, 2007, 8(12):973-982. doi: 10.1038/nrg2165 pmid: 17984973
[17]	MOSTERT D, WICKER E, DE JAGER M M, et al. A polyphasic approach reveals novel genotypes and updates the genetic structure of the banana fusarium wilt pathogen[J]. Microorganisms, 2022, 10(2):269.
[18]	LE D P, NGUYEN C P T, KAFLE D, et al. Surveillance, diversity and vegetative compatibility groups of Fusarium oxysporum f. sp. vasinfectum collected in cotton fields in Australia (2017 to 2022)[J]. Pathogens, 2022, 11(12):1537.
[19]	CZISLOWSKI E, FRASER‐SMITH S, ZANDER M, et al. Investigation of the diversity of effector genes in the banana pathogen, Fusarium oxysporum f. sp. cubense, reveals evidence of horizontal gene transfer[J]. Molecular plant pathology, 2018, 19(5):1155-1171.
[20]	ROCHA L O, LAURENCE M H, LUDOWICI V A, et al. Putative effector genes detected in Fusarium oxysporum from natural ecosystems of Australia[J]. Plant patholology, 2016, 65(6):914-929.
[21]	VAN DER DOES H C, LIEVENS B, CLAES L, et al. The presence of a virulence locus discriminates Fusarium oxysporum isolates causing tomato wilt from other isolates[J]. Environmental microbiology, 2008, 10(6):1475-1485.
[22]	SIMBAQUEBA J, CATANZARITI A, GONZÁLEZ C, et al. Evidence for horizontal gene transfer and separation of effector recognition from effector function revealed by analysis of effector genes shared between cape gooseberry- and tomato- infecting formae speciales of Fusarium oxysporum[J]. Molecular plant patholology, 2018, 19(10):2302-2318.
[23]	KASHIWA T, KOZAKI T, ISHII K, et al. Sequencing of individual chromosomes of plant pathogenic Fusarium oxysporum[J]. Fungal genetics and biology, 2017,98:46-51.
[24]	CZISLOWSKI E, ZEIL-ROLFE I, AITKEN E A B. Effector profiles of endophytic Fusarium associated with asymptomatic banana (Musa sp.) hosts[J]. International journal of molecular sciences, 2021, 22(5):2508.
[25]	郭立佳, 杨腊英, 彭军, 等. 香蕉枯萎病病原菌Six同源基因的鉴定[J]. 热带作物学报, 2013, 34(12):2391-2396.
[26]	LIEVENS B, HOUTERMAN P M, REP M. Effector gene screening allows unambiguous identification of Fusarium oxysporum f. sp. lycopersici races and discrimination from other formae speciales[J]. FEMS microbiology letters, 2009, 300(2):201-215.
[27]	CHAKRABARTI A, REP M, WANG B, et al. Variation in potential effector genes distinguishing Australian and non-Australian isolates of the cotton wilt pathogen Fusarium oxysporum f.sp. vasinfectum[J]. Plant pathology, 2011, 60(2):232-243.
[28]	ADUSEI-FOSU K, DICKINSON M. Development of pathogenicity assay and characterization of Fusarium oxysporum f. sp. elaeidis (FOE) based on Secreted In Xylem genes and EF-1α[J]. Journal of plant pathology, 2019, 101(4):1013-1024.
[29]	CARVALHAIS L C, HENDERSON J, RINCON-FLOREZ V A, et al. Molecular diagnostics of banana fusarium wilt targeting Secreted-in-Xylem genes[J]. Frontiers in plant science, 2019,10:547.
[30]	POON N K, TEO C H, OTHMAN R Y. Differential gene expression analysis of secreted in xylem (SIX) genes from Fusarium oxysporum f. sp. cubense tropical race 4 in Musa acuminata cv. berangan and potential application for early detection of infection[J]. Journal of general plant pathology, 2020, 86(1):13-23.
[31]	DOBBS J T, KIM M S, DUDLEY N S, et al. Whole genome analysis of the koa wilt pathogen (Fusarium oxysporum f. sp. koae) and the development of molecular tools for early detection and monitoring[J]. BMC genomics, 2020, 21(1):764.
[32]	BATSON A M, FOKKENS L, REP M, et al. Putative effector genes distinguish two pathogenicity groups of Fusarium oxysporum f. sp. spinaciae[J]. Molecular plant-microbe interactions, 2021, 34(2):141-156.
[33]	JENKINS S, TAYLOR A, JACKSON A C, et al. Identification and expression of Secreted In Xylem pathogenicity genes in Fusarium oxysporum f. sp. pisi[J]. Frontiers in microbiology, 2021,12:593140.
[34]	THANGAVEL R, PATTEMORE J A, REBIJITH K B, et al. Fusarium oxysporum f. sp. passiflorae infecting passionfruit in New Zealand in a changing taxonomic landscape[J]. Australasian plant pathology, 2021, 50(4):365-377.
[35]	THANGAVELU R, EDWINRAJ E, GOPI M, et al. Development of PCR-based race-specific markers for differentiation of Indian Fusarium oxysporum f. sp. cubense, the causal agent of Fusarium Wilt in banana[J]. Journal of fungi, 2022, 8(1):53.
[36]	CHU H H, TSAO W C, HUANG J W, et al. Development of specific primers for Fusarium oxysporum formae speciales rapae and matthiolae with an integrated multiplex pcr for distinguishing four formae speciales on brassicaceae[J]. Plant disease, 2024, 108(6):1632-1644.
[37]	NISHMITHA K, BASHYAL B M, DUBEY S C, et al. Molecular characterization of Indian races of Fusarium oxysporum f. sp. lentis (Fol) based on secreted in Xylem (SIX) effector genes and development of a SIX11 gene-based molecular marker for specific detection of Fol[J]. Archives of microbiology, 2024, 206(4):200.
[38]	WIDINUGRAHENI S, NIÑO-SÁNCHEZ J, DOES H C, et al. A SIX1 homolog in Fusarium oxysporum f.sp. cubense tropical race 4 contributes to virulence towards Cavendish banana[J]. Plos one, 2018, 13(10):e0205896.
[39]	FLEUR G, LISONG M, OSKAR O B, et al. The effector repertoire of Fusarium oxysporum determines the tomato xylem proteome composition following infection[J/OL]. Frontiers in plant science, 2015,doi:10.3389/fpls.2015.00967.
[40]	BLEKEMOLEN M C, CAO L, TINTOR N, et al. The primary function of Six5 of Fusarium oxysporum is to facilitate Avr2 activity by together manipulating the size exclusion limit of plasmodesmata[J]. Frontiers in plant science, 2022,13:910594.
[41]	杨腊英, 陈平亚, 郭立佳, 等. 尖孢镰刀菌古巴专化型中SIX2和SIX6基因敲除突变体的生物学特性[J]. 热带作物学报, 2018, 39(4):744-752.
[42]	YANG D, ZHANG X, MING Y, et al. Characterization of the high-quality genome sequence and virulence factors of Fusarium oxysporum f. sp. vasinfectum Race 7[J]. Journal of fungi, 2024, 10(4):242.
[43]	THATCHER L F, GARDINER D M, KAZAN K, et al. A Highly conserved effector in Fusarium oxysporum is required for full virulence on Arabidopsis[J]. Molecular plant-microbe interactions, 2012, 25(2):180-190.
[44]	KASHIWA T, INAMI K, FUJINAGA M, et al. An avirulence gene homologue in the tomato wilt fungus Fusarium oxysporum f. sp. lycopersici race 1 functions as a virulence gene in the cabbage yellows fungus F. oxysporum f. sp. conglutinans[J]. Journal of general plant pathology, 2013, 79(6):412-421.
[45]	侯兴蓉. SGE1和SIX8调控香蕉枯萎病菌致病力分子机制的研究[D]. 海口: 海南大学, 2018.
[46]	AYUKAWA Y, ASAI S, GAN P, et al. A pair of effectors encoded on a conditionally dispensable chromosome of Fusarium oxysporum suppress host-specific immunity[J]. Communications biology, 2021, 4(1):707.
[47]	AN B, HOU X, GUO Y, et al. The effector SIX8 is required for virulence of Fusarium oxysporum f.sp. cubense tropical race 4 to Cavendish banana[J]. Fungal biology, 2019, 123(5):423-430.
[48]	HAAPALAINEN M, LAITALA E, RÄMÖ S, et al. Pathogenicity and toxin production of different Fusarium oxysporum isolates infecting onion (Allium cepa L.)[J]. Annals of applied biology, 2022, 180(3):348-360.
[49]	LANUBILE A, ELLIS M L, MAROCCO A, et al. Association of effector Six6 with vascular wilt symptoms caused by Fusarium oxysporum on soybean[J]. Phytopathology, 2016, 106(11):1404-1412.
[50]	DUAN Y, QU W, CHANG S, et al. Identification of pathogenicity groups and pathogenic molecular characterization of Fusarium oxysporum f. sp. sesami in China[J]. Phytopathology, 2020, 110(5):1093-1104.
[51]	THANGAVELU R, RAJ E, PUSHPAKANTH P, et al. Draft genome resource of a novel virulent Fusarium oxysporum f. sp. cubense race 1 strain (VCG 0124) infecting cavendish (AAA) group of banana in India[J]. Plant disease, 2021, 105(9):2708-2710.
[52]	蔡文涌. 尖孢镰刀菌苜蓿专化型SIX效应基因的鉴定与表达分析[D]. 兰州: 兰州大学, 2022.
[53]	SAKANE K, UENO T, SHIGYO M, et al. Pathogenicity differentiation of Fusarium spp. causing fusarium basal rot and wilt disease in Allium spp.[J]. Pathogens, 2024, 13(7):591.
[54]	GAMBOA-BECERRA R, LÓPEZ-LIMA D, VILLAIN L, et al. Molecular and environmental triggering factors of pathogenicity of Fusarium oxysporum and F. solani isolates involved in the coffee corky-root disease[J]. Journal of fungi, 2021, 7(4):253.
[55]	TAYLOR A, ARMITAGE A D, HANDY C, et al. Basal rot of Narcissus: understanding pathogenicity in Fusarium oxysporum f. sp. narcissi[J]. Frontiers in microbiology, 2019,10:2905.
[56]	INUKAI S, KOCK K H, BULYK M L. Transcription factor-DNA binding: beyond binding site motifs[J]. Current opinion in genetics & development, 2017,43:110-119.
[57]	NIÑO-SÁNCHEZ J, CASADO-DEL CASTILLO V, TELLO V, et al. The FTF gene family regulates virulence and expression of SIX effectors in Fusarium oxysporum[J]. Molecular plant pathology, 2016, 17(7):1124-1139.
[58]	FLOR H H. Current status of the gene-for-gene concept[J]. Annual review of phytopathology, 1971, 9(1):275-296.
[59]	HOUTERMAN P M, MA L, VAN OOIJEN G, et al. The effector protein Avr2 of the xylem-colonizing fungus Fusarium oxysporum activates the tomato resistance protein I-2 intracellularly[J]. The plant journal, 2009, 58(6):970-978.
[60]	HOUTERMAN P M, CORNELISSEN B J C, REP M. Suppression of plant resistance gene-based immunity by a fungal effector[J]. Plos pathogens, 2008, 4(5):e1000061.
[61]	REP M, MEIJER M, HOUTERMAN P M, et al. Fusarium oxysporum evades I-3 -mediated resistance without altering the matching avirulence gene[J]. Molecular plant-microbe interactions, 2005, 18(1):15-23.
[62]	牛晓伟, 唐宁安, 范敏. 西瓜cDNA表达文库构建及镰刀菌致病因子FonSIX6互作蛋白的筛选和鉴定[J]. 园艺学报, 2012, 39(10):1958-1966.
[63]	NIU X, ZHAO X, LING K S, et al. The FonSIX6 gene acts as an avirulence effector in the Fusarium oxysporum f. sp. niveum - watermelon pathosystem[J]. Scientific reports, 2016, 6(1):28146.
[64]	DILLA-ERMITA C J, GOLDMAN P, ANCHIETA A, et al. Secreted in Xylem 6 (SIX6) mediates Fusarium oxysporum f. sp. fragariae race 1 avirulence on FW1 -resistant strawberry cultivars[J]. Molecular plant-microbe interactions, 2024, 37(6):530-541.
[65]	MA L, HOUTERMAN P M, GAWEHNS F, et al. The AVR2-SIX5 gene pair is required to activate I-2-mediated immunity in tomato[J]. New phytologist, 2015, 208(2):507-518.
[66]	彭存智, 常丽丽, 王丹, 等. 尖孢镰刀菌Six1d启动子的克隆及其在真菌分泌表达载体构建中的应用[J]. 热带作物学报, 2023, 44(6):1203-1213. doi: 10.3969/j.issn.1000-2561.2023.06.014
[67]	RATHORE A S, GUPTA K K, CHANDRASEKARAN J, et al. In silico identification of a promising inhibitor of Fusarium oxysporum f. sp. Lycopersici, Secreted in Xylem 1 protein[J]. Molecular diversity, 2024, 28(2):711.

宿主	效应因子		区分功能		参考文献
番茄	SIX1、SIX2、SIX3、SIX5		Fol		[26]
	SIX4		Fol生理小种Ⅰ		[26]
	SIX3点突变		Fol生理小种Ⅱ、Ⅲ		[26]
棉花	SIX6		澳大利亚Fov		[27]
油棕	EF-1α、SIX8、SIX9、SIX11		FOE		[28]
香蕉	SIX6		Foc生理小种Ⅰ		[29]
	SIX8a		Foc生理小种Ⅳ		[35]
	SIX1		Foc热带小种Ⅳ		[29]
	SIX1a		Foc热带小种Ⅳ		[35]
	SIX1b、SIX1c、SIX2、SIX8a		Foc热带小种Ⅳ		[30]
	SIX7a		Foc亚热带小种Ⅳ		[35]
	SIX8		Foc亚热带小种Ⅳ		[29]
相思树	SIX1、SIX6		Fo koae		[31]
菠菜	SIX4、SIX8、SIX14（SIX8、SIX9）		F. oxysporum f. sp. Spinaciae		[32]
豌豆	SIX1、SIX6、SIX7、SIX9、SIX10、SIX11、SIX12、SIX14		FOP生理小种Ⅰ		[33]
豌豆	SIX1、SIX6、SIX9、SIX13、SIX14（SIX1、SIX6、SIX13）		FOP生理小种Ⅱ		[33]
西番莲		EF-1α、β -微管蛋白、SIX6、SIX9		F. oxysporum f. sp. passiflorae	[34]
油菜、紫罗兰		SIX9、SIX14		F. oxysporum f. sp. rapae、F. oxysporum f. sp. matthiolae	[36]
扁豆		SIX11		F. oxysporum f. sp. lentis	[37]

宿主	效应因子		区分功能		参考文献
番茄	SIX1、SIX2、SIX3、SIX5		Fol		[26]
	SIX4		Fol生理小种Ⅰ		[26]
	SIX3点突变		Fol生理小种Ⅱ、Ⅲ		[26]
棉花	SIX6		澳大利亚Fov		[27]
油棕	EF-1α、SIX8、SIX9、SIX11		FOE		[28]
香蕉	SIX6		Foc生理小种Ⅰ		[29]
	SIX8a		Foc生理小种Ⅳ		[35]
	SIX1		Foc热带小种Ⅳ		[29]
	SIX1a		Foc热带小种Ⅳ		[35]
	SIX1b、SIX1c、SIX2、SIX8a		Foc热带小种Ⅳ		[30]
	SIX7a		Foc亚热带小种Ⅳ		[35]
	SIX8		Foc亚热带小种Ⅳ		[29]
相思树	SIX1、SIX6		Fo koae		[31]
菠菜	SIX4、SIX8、SIX14（SIX8、SIX9）		F. oxysporum f. sp. Spinaciae		[32]
豌豆	SIX1、SIX6、SIX7、SIX9、SIX10、SIX11、SIX12、SIX14		FOP生理小种Ⅰ		[33]
豌豆	SIX1、SIX6、SIX9、SIX13、SIX14（SIX1、SIX6、SIX13）		FOP生理小种Ⅱ		[33]
西番莲		EF-1α、β -微管蛋白、SIX6、SIX9		F. oxysporum f. sp. passiflorae	[34]
油菜、紫罗兰		SIX9、SIX14		F. oxysporum f. sp. rapae、F. oxysporum f. sp. matthiolae	[36]
扁豆		SIX11		F. oxysporum f. sp. lentis	[37]

尖孢镰刀菌SIX效应因子研究进展

Research Progress on SIX Effectors of Fusarium oxysporum

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

图/表 3

参考文献 67

相关文章 15

编辑推荐

Metrics

本文评价

关于本刊

作者中心

审者中心

在线期刊

联系我们

宿主	专化型	效应因子	致病因子	参考文献
香蕉	Foc热带生理小种Ⅳ	SIX1a	P	[38]
	Foc热带生理小种Ⅳ	SIX2、SIX6	P	[41]
	Foc热带生理小种Ⅳ	SIX8	P	[45]
番茄	Fol	SIX1、SIX3、SIX5、SIX6	P	[39]
棉花	Fov	SIX6	P	[42]
白菜	F. oxysporum f. sp. Conglutinans	SIX4	P	[44]

[1]	李雪君, 郭敬, 孙计平, 孙焕, 李芳芳, 平文丽, 李建华, 俎焕新, 李旭辉, 侯咏, 耿胜娜. 不同基因型烤烟对镰刀菌根腐病的抗性鉴定与评价[J]. 中国农学通报, 2024, 40(4): 126-131.
[2]	王越, 曹春梅, 陈汉, 王晓娇, 余乾鹏, 李学洋, 张志凯, 胡柏耿. 乌兰察布地区马铃薯疮痂病新型病原菌种类及致病性鉴定[J]. 中国农学通报, 2024, 40(32): 151-156.
[3]	廖设国, 赖福香, 刘玓玓, 郑弘朝, 郑然, 林慷祺, 范兰芬. 仙鹤草醇提取物对高致病性弧菌感染凡纳滨对虾的防治效果探究[J]. 中国农学通报, 2024, 40(23): 153-164.
[4]	石博, 谢媛媛, 关峰, 杨雪桐, 张景云, 王凯, 万新建. 苦瓜枯萎病抗病与感病品种根际土壤的微生物数量消长动态分析[J]. 中国农学通报, 2024, 40(22): 118-124.
[5]	付博, 王家哲, 任平, 李浩, 常青, 李英梅, 张锋. 猕猴桃黑头病菌的生物学特性及其致病性研究[J]. 中国农学通报, 2024, 40(22): 125-130.
[6]	孙婧, 成立新, 李蕴华, 岳林芳, 刘芳, 庞亚娟. 瑞香狼毒提取物对3种蔬菜枯萎病病原真菌的抑制作用[J]. 中国农学通报, 2024, 40(19): 115-119.
[7]	吴丽, 王永芬, 余宏伟, 丁明碧, 白亭亭, 李舒, 郑泗军. 物理诱变技术在提升有益微生物拮抗香蕉真菌病原菌方面的研究进展[J]. 中国农学通报, 2024, 40(18): 115-124.
[8]	陈新亮, 陈景益, 罗忠霞, 王章英, 房伯平, 王小斌, 黄立飞. 2株甘薯强致病力镰刀菌的室内药剂筛选[J]. 中国农学通报, 2023, 39(8): 106-111.
[9]	王欣, 沈亚伦, 陈思博, 李云鹏, 刘迦南. 16种植物源萃取物对2种植物病原菌的抑菌活性研究[J]. 中国农学通报, 2023, 39(6): 129-134.
[10]	李艳兰, 杨进成, 金红云, 罗志敏, 李祥, 李灶福, 张春帆, 胡新洲, 禹宗红, 刘坚坚, 高仕兰, 安正云, 王爱明, 蔡述江. 有机肥用量与配比对食粒豌豆3种病害防效的影响[J]. 中国农学通报, 2023, 39(4): 106-111.
[11]	陈文乐. 福建省三明地区非洲菊根腐病病原菌生物学特性与杀菌剂田间筛选[J]. 中国农学通报, 2023, 39(28): 107-111.
[12]	王珍珍, AZIMAKHAN Moldir, SERIKOVA Zhuldyz, KHASSANOV Vadim, TULEEVA Asiya, 张志凯, 吕典秋, 胡柏耿. 马铃薯育种材料在哈萨克斯坦地区的病毒鉴定和干腐病抗性研究[J]. 中国农学通报, 2023, 39(24): 127-134.
[13]	张晶晶. 半刺厚唇鱼源维氏气单胞菌的分离鉴定[J]. 中国农学通报, 2023, 39(20): 138-146.
[14]	张浩, 李海玉, 施松梅, 张忠润, 唐榕梓, 弓月芳, 邓文鑫, 杨正安. 2种黑籽南瓜响应枯萎病菌侵染的转录组学研究[J]. 中国农学通报, 2023, 39(18): 107-116.
[15]	董丽英, 刘沛, 刘树芳, 张先闻, 杨勤忠. 云南元江普通野生稻稻瘟病菌无毒基因鉴定与分析[J]. 中国农学通报, 2023, 39(18): 117-122.