Abstract: The cultivation of conventional Agaricusbisporus uses the straw for the main cultivating nourishment. The research uses vinegar dregs for the main cultivating nourishment and have obtained success. Bythis way , its mushroom time, picking, mushroom rate are improver than the conventional cultivation . Agaricusbisporus using vinegar dregs for noarishment are better than the conventional cultivation in thick protein, crude fiber, fat, carbonydrate. its contents are 40.2%, 5.8%, 3.4%, 30.1%, each quality targer attined the high quality target, now the cultivation using vinegar dregs for the main nourishment has moved towards the road of industry .