Abstract:

The aim of our study is to find out the regulation law of exogenous CNT (including cyclic Guanosine Monophosphate and cyclic Adenosine Monophosphate) on blood fat, sugar and protein in Haerbin white rabbits. We studied the dynamic variation law of different treatment groups in different time points within 4 days through injecting cGMP, cAMP and cGMP+cAMP. The results were as follows: blood fat content increased rapidly after injecting cGMP alone, about 17.63% in average, whereas after injecting cAMP the blood fat content decreased slightly. Increase of blood sugar content was only 1.79% in average after injecting cAMP alone, whereas after injecting cGMP the blood sugar content increased more than 10% in average. Increase of blood protein content was about 5% in average after injecting cGMP, cAMP and cGMP+cAMP. In addition, cGMP has a key role in accelerating fatty synthesis metabolism, blood fat content did not change during the first 10h of injecting cGMP, but significant effect on accelerating fatty synthesis was observed between 10 and 21h, and blood fat kept rising in certain rate after 21h of injection. But cAMP had a little effect in fat degradation. It has a fat degradation role with 45h of injecting cAMP, but changed into fat synthesis role between 45 and 65h, and the effect disappeared later. Furthermore, the effect CNT has little effect on blood protein, but gluconeogenesis resulted in the increase of blood sugar between 6 and 21h of injecting CNT. Finally, the dynamic variation law of these main metabolites provide beneficial theoretical basis in CNT regulation and control of the nutritive metabolic level in animals.