Abstract:

In order to understand the pathogenic of Eperythrozoon suis in Yanbian Area at this stage, BALB/c mice were divided into 3 groups: BALB/c mice in group 1 were injected with dexamethasone, BALB/c mice’s spleens in group 2 were removed and BALB/c mice in group 3 were normal. The BALB/c mice were artificially infected with E. suis by intraperitoneal injection. BALB/c mice infected with E. suis were identified by clinical observation of symptoms, blood smear, Giemsa staining and PCR method. And routine blood test was carried out. The results showed that the infection rates of the 3 groups reached their peaks in 8-10 d after infection. E. suis was disappeared in group 3 in 24 d after infection. E. suis was disappeared in group 1 in 32 d after infection. However, the infection rates of the group 2 were still high. Routine blood test showed that after infected with E. suis in each group, the total number of white blood cells was significantly increased (P<0.01), the total number of lymphocyte, red blood cells and the level of hemoglobin were significantly decreased (P<0.05). Red blood cells and the hematocrit was significantly decreased (P<0.01). This test confirmed that BALB/c mice could be infected by E. suis and the infected mice showed typical clinical symptoms.