Abstract: To analyze occurrence regularity of maize rough dwarf disease in Qiaocheng of Bozhou, we investigated systematically maize varieties, timing of sowing, cultivation patterns and meteorology regularity to analyze the impact of MRDV occurrence and popularity. The results showed that, the interaction impact of high temperature and drought and timing of sowing was main reason of MRDV occurrence and popularity. There was the lowest disease resistance of ‘Ludan981’, which the percentage of the disease incidence rate was 4.1%. The variety of ‘Jinsai6850’ had the highest disease resistance and disease incidence rate had only 0.9%. Because of high temperature and draught, there was the highest incidence rate of maize rough dwarf disease between in May and in June, the disease incidence rate was 21.2% in May, and 0.12% in June.