Abstract: To obtain the body temperature instance and sensitivity response to bacterial endotoxin of the Fujian rabbits, and to discuss whether the Fujian rabbits can be adapted to suit the use of pyrogen test. According to the standard pyrogen test from ‘Chinese Codex’, to choose Fujian rabbits with the eligible body temperature, which were administrated with three doses of endotoxin (5 Eu/mL, 10Eu/mL, 20Eu/mL) to analyze the sensitivity of these rabbits response to endotoxin. The 65.85% of the tested Fujian rabbits were up to the mustard and the body temperature of most rabbits was 38.5-39.5℃. The eligibity whereas under the Japanes White rabbit, WHBE and SPF New Zealand rabbits. The sensitivity of the Fujian rabbits reponse to bacterial endotoxin was positive correlativity to the dose of endotoxin, the big dose resulted to the high sensitivity. Through the test, it was known that most of the Fujian rabbits’ body temperature was steady, which had some sensitivity to the bacterial endotoxin. If the Fujian rabbits were fed in a standard way of laboratory animal, the quality of rabbits would more stable, and these rabbits would fit for the pyrogen test, which could broaden out the Fujian rabbits′ application field.