Abstract: Overuse of chemical fertilizer lead to serious problems regarding to the deterioration of vegetables and ecological environment. This study aimed to explore the effects of different fertilization managements on cauliflower yield and quality in Chongming modern agricultural park. Based on equal nitrogen amendments (N 600 kg/hm2), different chemical and organic fertilization combinations were used such as single chemical fertilizer, chemical fertilizer combined with commercial organic fertilizer, and combined with rotten pig manure and combined with rotten straw, respectively. The results showed that, compared with the control with only chemical fertilizer amended, all treatments with organic amendment could improve the yield and quality of cauliflower. The fertilizer combined with commercial organic fertilizer, rotten pig manure and rotten asparagus straw increased the yield 7.6%, 22.8% and 30.5%, respectively; and the vitamin C increased 10.70%, 12.66% and 10.34%, respectively; and the soluble sugar increased 18.18%, 26.70% and 39.58%, respectively; and the protein improved 26.39%, 27.58% and 17.06% respectively. The nitrate (NO3-N) content, however, decreased 53.21%, 51.01% and 17.84%, respectively. In conclusion, combining on organic and chemical fertilizer can improve the yield and quality of cauliflower effectively.