Abstract: To screen effective therapeutic agent, 5 fungicides, namely, prochloraz (45% ME), flusilazole (40% EC), tridemorph (75% EC), triadimefon (15% WP) and sulfur (95% WP) controlling powdery mildew of Hevea rubber were conducted by using conventional method in rubber nursery. The preliminary results showed that: after application 7 days sulfur (95% WP) was the best with control effect 83%, had a significant difference compared with other 4 kinds of agents. Tridemorph (75% EC) was better with control effect 60.2%. Flusilazole (40% EC), triadimefon (15% WP) and prochloraz (45% ME) were worse with control effect less than 50%. After application 30 days, sulfur (95% WP) was still the best with control effect 84.1%. Tridemorph (75% EC) was better with control effect 78.2%. Control effect of Flusilazole (40% EC) was 69.1%. There was no significant difference between the 3 agents. Prochloraz (45% ME) was the worst with control effect 33.0%. So, sulfur (95% WP) was still a significant therapeutic agent against powdery mildew of Hevea rubbe in rubber nursery. Tridemorph (75% EC) and flusilazole (40% EC) could be further development and utilization.