Abstract: The aim of the study were to explore response of different hybrid rice seeds to salt stress, screen hybrid rice combinations suitable for growing in saline soils. Thirty seeds of each of 8 hybrid rice combinations were treated with 0, 4, 8 and 12 g/L NaCl and incubated in Petri dishes for 7 days. Germination rate of hybrid seeds were counted in 4 and 7 days after germination, and bud length, main-root length, number of roots were investigated after 7 days. Salt tolerance (ST) of these combinations was evaluated by the relative damage rate. The results showed that germination rate, bud length, main-root length, number of roots were decreased along with increase of salt concentration．The germination rate was obviously inhibited by high concentration of salt solution (12 g/L), and the germination rate, bud length, main-root length, number of roots were decreased by 35.8%, 57.6%, 76.1% and 83.8%, respectively. However, the four characters didn’t show obvious decrease under lower salt concentration (4, 8 g/L), and inversely they showed increase in some combinations. Salt stress had greater influence on number of roots than bud length and main- root length, in which number of roots decreased more rapidly along with rising of salt concentration.‘Gui-yuan-you 500’,‘II-you 1040’,‘II-you 1050’and‘Yong-you 12’were screened out as salt tolerance hybrid combinations with tolerant score of 1, 1, 3 and 3, respectively. The concentration of salt solution (12 g/L) was suitable to screen ST for hybrid seeds at germination stage, and the relative damage rate was recommended as an appropriate index for evaluation of ST.