Abstract: In order to investigate the effect of leaf fertilizer Penshibao on pesticide residue and activities of antioxidant enzyme in vegetables, the study investigated the effect of such fertilizer on three pesticide residue (imidacloprid, chlorpyrifos and beta-cypermethrin) and the activities of superoxidedismutase (SOD), catalase (CAT), peroxidase(POD) in Brassica albograbra under outdoor cultivation conditions. The results showed that, compared with control, the leaf fertilizer Penshibao could promote degradation of imidacloprid, chlorpyrifos and beta- cypermethrin in the vegetable while the extents were affected by the concentration and time of application. Penshibao increased activities of CAT and SOD in Brassica albograbra under the stress of betacypermethrin as well as activities of CAT under the stress of chlorpyrifos while no significant effects of the same fertilizer on activities of POD appeared under the stress of chlorpyrifos. Under the stress of imidacloprid, Penshibao increased activities of POD in Brassica albograbra significantly while its effects on activities of SOD under the same pesticide were not significant.