Abstract: In order to make effective utilization of climate resources, avoid disadvantages caused by climate change, and ensure the safety of food and characteristics crops growing, based on the climate data from 1971 to 2010 of 9 representative meteorological stations of Guangdong Province, the features had been analyzed about the spatial and temporal variation of temperature, precipitation and sunshine in recent 40 years. The results indicated that the average temperature had increased in each climatic zone of Guangdong Province since 1976 by an obvious trend, and the mutation point appeared in 1989, the average temperature had been declining since 2007; the average temperature also rose in four seasons, especially in winter and autumn, from north to south, the average temperature increased mostly in winter, and changes were small in summer; the heat resources increased significantly after 1990. The annual precipitation showed a decreasing trend, the precipitation gradually reduced in winter and spring from north to south, and increased in summer and autumn. Potential evapotranspiration was the lowest in the 1980s and was the highest in the early 21st century, the increasing was most obvious in winter. The change of the sunshine percentage decreased for 40 years. Climate change had a certain impact on crop growing, production, quality, plant layout and meteorological disasters, such as drought.