Abstract: To provide a theoretical basis for pitaya ecological cultivation, the effects of pitaya and soybean intercropping pattern on the ecological factors and economic benefit were evaluated by red skin red meat Hylocereus undatus intercropping with‘edamame No.5’or‘Huaxia No.3’. Results indicated that pitaya and soybean intercropping pattern could improve the soil physical characteristics, the soil volume weight reduced by 5.07%-7.97%, total porosity and moisture content increased by 5.51%-8.66% and 56.40%-59.66%, respectively. Also the soil organic matter, total N, available nitrogen and rapidly available potassium respectively increased by 36.61%-42.62%, 75.67%-77.03%, 48.57%-61.92%, and 81.64%-103.12%, but the available phosphorus decreased by 31.89%-35.99%. The intercropping pattern also improved the microecological environment in pitaya orchard, the air temperature and soil temperature reduced by 2℃ and 3℃, respectively, and the relative humidity increased by 4%-6%. The pitaya and soybean intercropping pattern has certain advantages and could significantly improve the economic benefit of pitaya orchard with a benefit raise of 17.86%-24.93%.