Abstract: This paper analyzed the Impact of RMB exchange rate changes on Chinese Food Security based on China general equilibrium financial model. The results show that Under existing conditions of China's economic growth, RMB appreciation of 5%, 10%, 20%, China's economic will suffer relatively long-lasting negative results. Same as the industrial sectors, RMB appreciation also generated seriously negative impact to the agriculture sector, such as decrease of product output, employment, investment and output prices. It endanger agricultural production and supply, has closely relationship with China's food security. In fact, since 2005, 22 percent of real appreciation of RMB has implemented. Over the past few years, in addition to grain production, China's agricultural production suffered a lot of price risk, in theory, behind the price risk, May be the result of the appreciation of RMB, Therefore, in the RMB appreciation process, we must pay close attention to China's agricultural production, especially grain production safety.