Abstract: Abstract: [Objective] In order to explore the application effect of slowed controlled-release fertilizers on indica-japonicabrid rice productivity, [Method] a field experiment was conducted to investigate the responses to different application rate of controlled release fertilizers and regular fertilizer to rice grain yield, quality and economic benefits of Yongyou 12. Five fertilizer treatments were compared, including control (CK), regular fertilizer (RF), 100% slowed controlled-release fertilizers (100% CRF), 80% slowed controlled-release fertilizers (80% CRF) and 60% slowed controlled-release fertilizers (60% CRF). [Result] The research achievement shows overall, 100% CRF had the highest improvement on rice grain yield, economic indicator, rice quality and economic benefits, which can increase the head rice rate and alkali spreading value, but decrease the chalky rice rate and crude protein content. 80% CRF had the similar effect on rice as RF, but 60% CRF had a lower improvement on rice grain yield, plant height, effective panicles and economic benefits compared with RF. [Conclusion] The results indicate that nitrogen is the most important element which controls the rice grain yield and quality, thus nitrogen application rate should be firstly considered when the slowed controlled-release fertilizers is developed and generalized.