Abstract: In order to classify the leaf pollution tolerance of main fruit trees in south Xinjiang, use fruit tree leaves as materials, the authors respectively detect and compare the ascorbic acid, total chlorophyll content, pH value, leaf relative water content of different fruit trees under the natural polluting condition, adopted Singh formula to estimate the leaf dust pollution tolerance of main fruit trees in south Xinjiang. The results showed that leaf chlorophyll content of the samples ranged from 33.48 to 57.03 SPAD, while Qiufu had the highest chlorophyll content, the fig had the lowest value. The pH values ranged from 3.67 to 6.60, and leaves of most fruit trees were acidic; leaves of figs, cherry, Cydonia oblonga, white mulberry and jujube were close to neutral. The relative leaf water content ranged from 39.22% to 77.01%, and that of grape, Yili fragrant pear, Jujuli, apricot, small white apricot and fig was high, but Korla fragrant pear had the lowest leaf relative water content. Ascorbic acid content varied from 0.43 to 2.01 mg/g, walnut had the highest ascorbic acid content; plums, figs, hawthorn had the lowest ascorbic acid content. Applying Singh formula to calculate APTI value which depicted plant pollution tolerance and using clustering analysis could classify the leaf dust pollution tolerance of main fruit trees in south Xinjiang as best, good, ordinary, worse and worst.