Abstract: The aim is to evaluate the residue behavior and environmental safety of cyprodinil applied in strawberry under facility cultivation. According to the trial standard of pesticide residue, we studied the degradation dynamics and final residue of cyprodinil applied in strawberry with the field test method. Based on the residual analysis results, the drug-use condition was adjusted in actual production, then the best safety interval was explored. The results showed that when the drug was applied one time with 800 times diluents, the degradation half- lives of cyprodinil in strawberry was 3.180 d. Along with the increase of application concentration and application times, the final residue of cyprodinil and dietary risk increased, thus the safety interval should be appropriately extended.