Abstract: To study the alleviated effect of Se on single pollution of Pb and As in Chinese cabbage, seed germination experiments were performed to investigate the effect of exogenous Se (12.5、25、50、75、100 mg/kg) on single pollution of Pb (600、800、1000 mg/kg) and As (80、100 mg/kg) in seed germination and seedling growth of Chinese cabbage. The results showed that different concentrations of Se dramatically increased the germination rate, germination potential, root length, shoot length and the fresh weight under Pb and As stress, which indicated that exogenous Se application could effectively alleviate Pb and As toxicity to Chinese cabbage. For the single pollution of Pb of the three concentrations, the appropriate Se concentrations were 12.5, 25 and 50 mg/kg. For the single pollution of As of the two concentrations, the appropriate Se concentrations were 25 and 100 mg/kg.