Abstract: The output of horse mackerel in the world has declined since 2010. The research on the fishing grounds of horse mackerel and the reserve fishery should been strengthened. According to the statistical data of the horse mackerel in the sea area of Cape Verde coastal of central Eastern Central Atlantic of fishing yield in Chinese vessels from January to August 2012 , from December The output of horse mackerel in the world has declined since 2010. So, the research on fishing grounds of horse mackerel and reserve fishery should be strengthened. In this study, the yield data of horse mackerel and marine environmental data obtained by remote sensing in the sea area of Cape Verde coast in Central Atlantic from January to August in 2012, from December 2013 to June 2014 and from January to August in 2015 were used. The monthly changes of average catch per unit effort (CPUE), spatial-temporal change of central fishing ground, as well as the correlations of CPUE with environmental factors including concentration of chlorophyll a, sea surface temperature (SST), longitude and latitude were analyzed by using production-centroid method, statistical interpolation, and generalized additive model (GAM). The results showed that the monthly change of average CPUE from December 2013 to June 2014 was similar to those from January to August in 2015, both of which showed large difference to that from January to August in 2012. The monthly change of average CPUE varied largely in different years. The center of fishery production in each year reached the southernmost tip of the fishing ground in April or May. Before April or May, the center basically moved from north to south; and after April or May, the center moved from south to north. GAM analysis showed that the optimum SST was 19.5-21℃, the optimum concentration of chlorophyll a was 5.473-6.685 mg/m3, the optimum longitude concentrated near 16°30''W and the latitude concentrated near 18°N. CPUE exhibited insignificant correlations with concentration of chlorophyll a and longitude (P>0.05); extremely significant correlation with SST (P<0.01); and significant correlation with latitude (P<0.05). In conclusion, taking this fishing ground only for horse mackerel needs further studies.