Abstract: The paper aims to promote the regionalization and specialized production of tea industry in Sichuan Province. Based on the tea production data, we analyzed the evolution track of production center and the spatial structure of tea industry in Sichuan, by using gravity center model and ESDA method. The results show that: (1) the tea production developed rapidly, and has formed 3 major production areas in southern Sichuan, western Sichuan and northeast Sichuan; (2) the migration scale of gravity center of tea plantation area in Sichuan is small, and the gravity center is expanded to the southeast; (3) the Moran’s index range of tea garden in Sichuan is generally from 0.35 to 0.457, indicating significantly positive spatial autocorrelation and high spatial agglomeration characteristics; (4) regions with H-H mainly are those most suitable areas located in Wumeng mountain area, Qionglai mountain area and Qinba mountain area, regions with L-L mainly belong to the unsuitable area or low suitable area in the northwest plateau of Sichuan or mid-Sichuan hilly region. Since 2000, the agglomeration trend in the tea production area of northeast Sichuan decreases significantly, while in southern and western Sichuan, there is a marked trend of aggregation. The structure of tea production in Sichuan is a physiological suitable one based on natural resources endowment, in the future development, industrial scale, leading enterprises, regional brands, alternative industries, support policies and other factors could be the major shaping power of spatial structure evolution of tea production in Sichuan.