MSTN and FGF5 Gene Editing Does Not Affect Estrus Synchronization of Cashmere Goats

doi:10.11924/j.issn.1000-6850.casb17080082

Abstract

Abstract: In this study, we aim to compare the responses of wild-type cashmere goats withMSTN- orFGF5-editing cashmere goats on the hormones for estrus synchronization, then find out the difference of estrus synchronization efficiency between the wild-type and the gene-editing cashmere goats. The goats were treated with the same method (CIDR + PG) in the breeding season. The results showed that the estrus synchronization rate of the wild-type cashmere goats was 100 % after the treatment, and that of the gene-editing goats was also 100% . Moreover, the MSTN- and FGF5- editing goats showed no significant difference in the estrus synchronization efficiency, and also showed no significant difference in that with the wild-type goats. The results confirmed thatMSTN andFGF5 gene editing did not affect the reproductive performance of cashmere goats. The results provide an experimental basis for the application of gene editing animals.

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