Abstract: In order to master the research progress of the abortion mechanism of seedless grape and clarify the research findings and problems, the authors summarized recent research results at home and abroad focusing on 5 aspects of cytology, physiology, biochemistry, heredity of seedless characters, molecular markers of seedless gene and functions of related gene of seedless, and found that researches on genes types, gene interactions and regulatory network during grape embryo development and abortion were relatively deficient. Finally, the authors pointed out that the combination of multi- omics would promote the research on the abortion mechanism of seedless grape.