Abstract: The paper aims to provide model reference and case reference for regional scale development of circular agriculture combined with crop and animal production, which could achieve coordinated and efficient utilization of agricultural waste resources, by summarizing the typical models of manure treatment in Jiangsu. Taking the government-led Wujin District Agricultural Waste Comprehensive Treatment Center (Lijia Station) as an example, we introduced the background and structure of the combination model, analyzed the key technical components, economic, ecological and social benefits, and clarified the operational mechanism. The results showed that: the construction of collecting service system formed a community of interests among breeding industry, planting industry, third-party service organizations, government and the publics, and solved the bottleneck problem of harmless treatment and resource utilization of small scattered breeding manure, and promoted the process of “rural revitalization” of “beautiful environment, rich farmers”. The government-led centralized treatment mode of breeding manure explored in Jiangsu is more representative and demonstrative value for construction and development of regional scale circular agriculture integrated crop and animal production.