SnRK2 Gene Family in Plants: A Review

doi:10.11924/j.issn.1000-6850.casb2022-0923

Abstract

Abstract:

Sucrose non-fermenting 1-related protein kinase 2(SnRK2) is a ubiquitous protein kinase in plants. It belongs to the Ser/Thr class of protein kinases, and can play a role in various signal transductions. In order to study the role of SnRK2 protein kinase in plant stress resistance, this study analyzed the characteristics and research process of SnRK2 gene family, summarized the functions of SnRK2 gene in regulating stomatal size of plant leaf, responding to drought stress and salt stress, and responding to seed germination and development. It was pointed out that SnRK2 gene played a role in various signal transductions, which could effectively improve plant stress resistance. It is of great significance for ABA response, plant growth and development, and it provides a reference basis for future research on the molecular mechanism of SnRK2 and plant variety cultivation.

Key words: SnRK2 gene family, sucrose non fermenting1 related protein kinase, plant stress resistance, abiotic stress, gene function

LI Na, ZHANG Wenyu, SUN Gang, SONG Han, HU Xiuqin, XIN Jie, WANG Zhen. SnRK2 Gene Family in Plants: A Review[J]. Chinese Agricultural Science Bulletin, 2023, 39(30): 108-113.

References 56

[1]	刘子茜, 朱雅欣, 伍国强, 等. SnRK2在植物响应逆境胁迫和生长发育中的作用[J]. 生物工程学报, 2022, 38(1):89-103.
[2]	YOSHIDA R, UMEZAWA T, MIZOGUCHI T, et al. The regulatory domain of SRK2E/OST1/SnRK2.6 interacts with ABI1 and integrates abscisic acid (ABA) and osmotic stress signals controlling stomatal closure in Arabidopsis[J]. The journal of biological chemistry, 2006, 281(8):5310-5318. doi: 10.1074/jbc.M509820200 URL
[3]	马宗桓, 毛娟, 李文芳, 等. 葡萄SnRK2家族基因的鉴定与表达分析[J]. 园艺学报, 2016, 43(10):1891-1902. doi: 10.16420/j.issn.0513-353x.2015-0912
[4]	王海波. 小桐子SnRK2基因家族的全基因组鉴定及特征分析[J]. 分子植物育种, 2016, 14(9):2319-2329.
[5]	刘涛, 王萍萍, 何红红, 等. 草莓SnRK2基因家族的鉴定与表达分析[J]. 农业生物技术学报, 2019, 27(12):2150-2163.
[6]	BOUDSOCQ M, BARBIER-BRYGOO H, LAURIERE C. Identification of nine sucrose nonfermenting 1-related protein kinases 2 activated by hyperosmotic and saline stresses in Arabidopsis thaliana[J]. Journal of biological chemistry, 2004, 279(40):41758-41766. doi: 10.1074/jbc.M405259200 URL
[7]	WU Z, CHENG J, HU F, et al. The SnRK2 family in pepper (Capsicum annuum L.): genome-wide identification and expression analyses during fruit development and under abiotic stress[J]. Genes genomics, 2020, 42(10):1117-1130. doi: 10.1007/s13258-020-00968-y
[8]	ANDERBERG R J, WALKER-SIMMONS M K. Isolation of a wheat cDNA clone for an abscisic acid-inducible transcript with homology to protein kinases[J]. Proceedings of the national academy of sciences of the United States of America, 1992, 89(21):10183-10187. doi: 10.1073/pnas.89.21.10183 pmid: 1438207
[9]	CHEESEMAN J M. Mechanisms of salinity tolerance in plants[J]. Plant physiology, 1988, 87(3):547-550. doi: 10.1104/pp.87.3.547 pmid: 16666181
[10]	周颖, 白艳红, 王钰, 等. 丹参SnRK2基因家族的鉴定与表达[J]. 分子植物育种, 2022, 20(7):2233-2243.
[11]	宋雪晴, 诸葛强. 植物SnRK2基因家族研究进展[J]. 分子植物育种, 2016, 14(4):870-877.
[12]	SHIN R, ALVAREZ S, BURCH AY, et al. Phosphoproteomic identification of targets of the Arabidopsis sucrose nonfermenting-like kinase SnRK2. 8 reveals a connection to metabolic processes[J]. Proceedings of the national academy of sciences, 2007, 104(15):6460-6465. doi: 10.1073/pnas.0610208104 URL
[13]	DIÉDHIOU C J, POPOVA O V, DIETZ K J, et al. The SNF1-type serine-threonine protein kinase SAPK4regulates stress-responsive gene expression in rice[J]. BMC plant biology, 2008, 8(1):1-13. doi: 10.1186/1471-2229-8-1
[14]	UMEZAWA T, YOSHIDA R, MARUYAMA K, et al. SRK2C, a SNF1-related protein kinase 2, improves drought tolerance by controlling stress-responsive gene expression in Arabidopsis thaliana[J]. Proceedings of the national academy of sciences, 2004, 101(49):17306-17311. doi: 10.1073/pnas.0407758101 URL
[15]	MAO X, ZHANG H, TIAN S, et al. TaSnRK2. 4, an SNF1-type serine/threonine protein kinase of wheat (Triticum aestivum L.), confers enhanced multistress tolerance in Arabidopsis[J]. Journal of experimental botany, 2010, 61(3):683-696. doi: 10.1093/jxb/erp331 URL
[16]	KOBAYASHI Y, YAMAMOTO S, MINAMI H, et al. Differential activation of the rice sucrose nonfermenting1-related protein kinase2 family by hyperosmotic stress and abscisic acid[J]. The plant cell, 2004, 16(5):1163-1177. doi: 10.1105/tpc.019943 URL
[17]	BELDA-PALAZON B, ADAMO M, VALERIO C, et al. A dual function of SnRK2 kinases in the regulation of SnRK1 and plant growth[J]. Nature plants. 2020, 6(11):1345-1353. doi: 10.1038/s41477-020-00778-w
[18]	WANG P, ZHAO Y, LI Z, et al. Reciprocal regulation of the TOR kinase and ABA receptor balances plant growth and stress response[J]. Molecular cell, 2018, 69(1):100-106. doi: S1097-2765(17)30930-9 pmid: 29290610
[19]	孙聪聪. 白菜、甘蓝和拟南芥SnRK家族蛋白激酶比较分析与功能研究[D]. 杨凌: 西北农林科技大学, 2017.
[20]	SOON F F, NG L M, ZHOU X E, et al. Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases[J]. Science, 2012, 335(6064):85-88. doi: 10.1126/science.1215106 URL
[21]	PUNKKINEN M, MAHFOUZ M M, FUJII H. Chemical activation of Arabidopsis SnRK2.6 by pladienolide B[J]. Plant signaling & behavior, 2021, 16(5):1885165.
[22]	TAKAHASHI Y, ZHANG J, HSU P K, et al. MAP3Kinase-dependent SnRK2-kinase activation is required for abscisic acid signal transduction and rapid osmotic stress response[J]. Nature communications, 2020, 11(1):12. doi: 10.1038/s41467-019-13875-y pmid: 31896774
[23]	WANG P, XUE L, BATELLI G, et al. Quantitative phosphoproteomics identifies SnRK2 protein kinase substrates and reveals the effectors of abscisic acid action[J]. Proceedings of the national academy of sciences of the United States of America, 2013; 110(27):11205-10. doi: 10.1073/pnas.1308974110 pmid: 23776212
[24]	SOMA F, MOGAMI J, YOSHIDA T, et al. ABA-unresponsive SnRK2 protein kinases regulate mRNA decay under osmotic stress in plants[J]. Nature plants, 2017; 3:16204. doi: 10.1038/nplants.2016.204 pmid: 28059081
[25]	TIAN S, MAO X, ZHANG H, et al. Cloning and characterization of TaSnRK2.3, a novel SnRK2 gene in common wheat[J]. Journal of experimental botany, 2013, 64(7):2063-2080. doi: 10.1093/jxb/ert072 pmid: 23630328
[26]	马天意. 油菜保卫细胞功能性SnRK2基因鉴定及BnSnRK2.6-2C氧化还原位点鉴定[D]. 哈尔滨: 东北林业大学, 2017.
[27]	SHI Y, LIU X, ZHAO S, et al. The PYR-PP2C-CKL2 module regulates ABA-mediated actin reorganization during stomatal closure[J]. The new phytologist, 2022, 233(5):2168-2184. doi: 10.1111/nph.v233.5 URL
[28]	陈思思. H_2S介导的S-硫巯基修饰调节SnRK2.6活性促进ABA诱导的气孔闭合[D]. 杨凌: 西北农林科技大学, 2020.
[29]	MUSTILLI A C, MERLOT S, VAVASSEUR A, et al. Arabidopsis OST1 protein kinase mediates the regulation of stomatal aperture by abscisic acid and acts upstream of reactive oxygen species production[J]. Plant cell, 2002, 14(12):3089-3099. doi: 10.1105/tpc.007906 URL
[30]	魏雪莹. SnRK2.6蛋白激酶对高温强光下番茄气孔运动的调节作用[D]. 沈阳: 沈阳农业大学, 2020.
[31]	FUJITA Y, YOSHIDA T, YAMAGUCHI-SHINOZAKI K. Pivotal role of the AREB/ABF-SnRK2 pathway in ABRE-mediated transcription in response to osmotic stress in plants[J]. Physiol plant, 2013, 147(1):15-27. doi: 10.1111/j.1399-3054.2012.01635.x pmid: 22519646
[32]	周正, 白玲, 余燕, 等. 持续水分胁迫对丹参茎叶酚酸含量及其抗氧化活性的影响[J]. 西北植物学报,. 2022, 42(3):435-443.
[33]	张永恒. 茶树SnRK2家族基因的鉴定及CsSnRK2.5的功能研究[D]. 杨凌: 西北农林科技大学, 2019.
[34]	ZHANG Y H, WAN S Q, WANG W D, et al. Genome-wide identification and characterization of the CsSnRK2 family in Camellia sinensis[J]. Plant physiology and biochemistry, 2018, 132:287-296. doi: 10.1016/j.plaphy.2018.09.021 URL
[35]	向殿军, 满丽莉, 王庆祥, 等. 燕麦蛋白激酶基因AsSnRK2.10的克隆及非生物胁迫响应分析[J]. 农业生物技术学报, 2020, 28(11):1923-1935.
[36]	HOLAPPA L D, RONALD P C, KRAMER E M. Evolutionary analysis of snf1-related protein kinase2 (SnRK2) and calcium sensor (SCS) gene lineages, and dimerization of rice homologs, suggest deep biochemical conservation across angiosperms[J]. Frontiers in plant science, 2017, 8:395. doi: 10.3389/fpls.2017.00395 pmid: 28424709
[37]	ZHANG Y, WAN S, LIU X, et al. Overexpression of CsSnRK2. 5 increases tolerance to drought stress in transgenic Arabidopsis[J]. Plant physiology and biochemistry, 2020, 150:162-170. doi: 10.1016/j.plaphy.2020.02.035 URL
[38]	白戈, 杨大海, 费明亮, 等. 烟草SnRK2基因家族的克隆及表达分析[J]. 分子植物育种, 2021:1-13.
[39]	王瑞姣. 矮秆波兰小麦SnRK2.10和SnRK2.11基因的功能分析[D]. 雅安: 四川农业大学, 2018.
[40]	齐琪, 马书荣, 徐维东. 盐胁迫对植物生长的影响及耐盐生理机制研究进展[J]. 分子植物育种, 2020, 18(8):2741-2746.
[41]	GUPTA B, HUANG B. Mechanism of salinity tolerance in plants: physiological, biochemical, and molecular characterization[J]. International journal of genomics,2014,2014(2014):12.
[42]	KAWA D, MEYER A J, DEKKER H L, et al. SnRK2 protein kinases and mrna decapping machinery control root development and response to salt[J]. Plant physiol., 2020, 182(1):361-377. doi: 10.1104/pp.19.00818 pmid: 31570508
[43]	SONG X, YU X, HORI C, et al. Heterologous overexpression of poplar SnRK2 genes enhanced salt stress tolerance in Arabidopsis thaliana[J]. Frontiers in plant science, 2016, 7:612.
[44]	ZHANG M, LIU L, CHEN C, et al. Heterologous expression of a Fraxinus velutina SnRK2 gene in Arabidopsis increases salt tolerance by modifying root development and ion homeostasis[J]. Plant cell reports, 2022, 41(9):12.
[45]	LIU Z, GE X, YANG Z, et al. Genome-wide identification and characterization of SnRK2gene family in cotton (Gossypium hirsutum L.)[J]. BMC genetics, 2017, 18(1):1-14. doi: 10.1186/s12863-016-0468-0 URL
[46]	ZHANG H, MAO X, WANG C, et al. Overexpression of a common wheat gene TaSnRK2.8 enhances tolerance to drought, salt and low temperature in Arabidopsis[J]. Plos one, 2010, 5(12):e16041. doi: 10.1371/journal.pone.0016041 URL
[47]	WU G Q, LIU Z X, XIE L L, et al. Genome-wide identification and expression analysis of the BvSnRK2genes family in sugar beet (Beta vulgaris L.) under salt conditions[J]. Journal of plant growth regulation, 2021, 40(2):519-532. doi: 10.1007/s00344-020-10119-y
[48]	YU X, TAKEBAYASHI A, DEMURA T, et al. Differential expression of poplar sucrose nonfermenting1-related protein kinase 2 genes in response to abiotic stress and abscisic acid[J]. Journal of plant research, 2017, 130(5):929-940. doi: 10.1007/s10265-017-0952-2 pmid: 28550412
[49]	BAI J, MAO J, YANG H, et al. Sucrose non-ferment 1 related protein kinase 2 (SnRK2) genes could mediate the stress responses in potato (Solanum tuberosum L.)[J]. BMC genetics, 2017, 18(1):41. doi: 10.1186/s12863-017-0506-6 URL
[50]	ZHANG F, CHEN X J, WANG J H, et al. Overexpression of a maize SNF-related protein kinase gene, ZmSnRK2. 11, reduces salt and drought tolerance in Arabidopsis[J]. Journal of integrative agriculture, 2015, 14(7):1229-1241. doi: 10.1016/S2095-3119(14)60872-8
[51]	张永恒, 万思卿, 陈江飞, 等. 茶树CsSnRK2.1、CsSnRK2.2基因的克隆及在非生物胁迫中的响应[J]. 茶叶科学, 2018, 38(2):183-192.
[52]	李荣, 冯月娟, 王舰, 等. 马铃薯StSnRK2.4基因的序列分析及其在非生物胁迫下的表达分析[J]. 分子植物育种, 2021, 19(22):7327-7336.
[53]	吴珊. 拟南芥AtSnRK2.4和AtMYB21基因参与非生物逆境胁迫的功能研究[D]. 哈尔滨: 东北林业大学, 2017.
[54]	FENG C Z, CHEN Y, WANG C, et al. Arabidopsis RAV1 transcription factor, phosphorylated by SnRK 2 kinases, regulates the expression of ABI3, ABI4, and ABI5 during seed germination and early seedling development[J]. The plant journal, 2014, 80(4):654-668. doi: 10.1111/tpj.2014.80.issue-4 URL
[55]	NAKASHIMA K, FUJITA Y, KANAMORI N, et al. Three Arabidopsis SnRK2 protein kinases, SRK2D/SnRK2.2, SRK2E/SnRK2.6/OST1 and SRK2I/SnRK2.3, involved in ABA signaling are essential for the control of seed development and dormancy[J]. Plant and cell physiology, 2009, 50(7):1345-1363. doi: 10.1093/pcp/pcp083 URL
[56]	SU D, DEVARENNE T P. In vitro activity characterization of the tomato SnRK1 complex proteins[J]. Biochimica et biophysica acta (BBA) proteins and proteomics, 2018, 1866(8):857-864. doi: 10.1016/j.bbapap.2018.05.010 URL