Abstract: Based on the main characters of internationalization of seed business, its limiting factors in China were analyzed in this paper. Considering the main problems existing in the development of seed business, some tactics were submitted based on the mechanism of enterprises, the application of new breeding technique, the developing direction of seed business and market management. The tactics included in changing the mechanism of our enterprises, paying more attention to the development of key enterprises, giving more support to the research of seed production, accelerating the application of biotechnology to plant breeding, strengthening the management to seed business and promoting the level of seed internationalization.