Abstract:

Cloning and sequencing the Liver X Receptors α cDNA from porcine liver tissues by RT-PCR, the coding region length was 1344bp, coding 447 Amino Acids, Zinc finger and ligand-binding domain of nuclear hormone receptor are found based on the Pfam database, phylogenetic result showed that the LXRα genes in Mammalia clade were very conserved, the genetic distance between the Mammalia clade and non-Mammalia clade including chicken and zebrafish, LXRα mRNA level were detected in the adipose tissues showed that LXRα mRNA expression increased from 3-month to 12-month, the mRNA level was the most high in 9-month in large white pig, but the LXRα mRNA expression were detected in 9 month, and the expression in 12-month was high in crossed-bred wild pig.