Abstract: For comprehensive understanding the harm of Euphorbia maculata to native species and its invasive mechanism, it were conducted that the allelopathic effects of aqueous shoot extracts from Euphorbia maculata on seed germination and seedling growth in four vegetable species. The results showed aqueous shoot extracts of Euphorbia maculata could inhibit seed germination speed in all the four species, reduce seed germination rate in Lycopersicon esculentum, Schizonepeta tenuifolia and Capsicum frutescents, and its effects increased with the increase of extracts concentration, while having no effects on seed germination of Edible umaranth. High concentration (0.4g/ml) of extracts of Euphorbia maculata intensively inhibited root growth in all four species, while it stimulated shoot growth in Edible umaranth, Capsicum frutescents and Schizonepeta tenuifolia, and showed same influencing pattern on root/shoot rates as seed germination speed.