Abstract: Effects of hydration-dehydration on seedling drought resistance in dry chili was studied by the repeated drought method; aim to screen the best treatment of hydration- dehydration for enhancing the seedling drought resistance of dry chili. The results showed that hydration-dehydration can effectively increase the seedling drought resistance of dry chili. Hydration-dehydration treatment can promote the germination of the seeds. The repeated drought seedling survival rates of the treatment group significantly exceeded the control. Treatment cycles have no impact to the repeated drought seedling survival rate, but the soaked time showed a distinct role. 6 hours is the best soaked time for dry hot pepper seeds.