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Chinese Agricultural Science Bulletin ›› 2015, Vol. 31 ›› Issue (8): 6-11.doi: 10.11924/j.issn.1000-6850.casb14100088

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Recent Progress on Regulatory Mechanisms of Deer Antler Ossification

Zhang Wei, Chu Wenhui, Li Chunyi   

  1. (Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences/State Key Laboratory for Molecular Biology of Special Economic Animals, Changchun 130000)
  • Received:2014-10-22 Revised:2015-03-01 Accepted:2014-12-29 Online:2015-04-07 Published:2015-04-07

Abstract: Deer antlers are unique mammalian bony organs with periodic regeneration. Development of deer antlers initiate from antlerogenic periosteum, and the processes of ossification of deer antlers include intramembranous, transitional and modified endochondral ossification. Multiple regulatory factors and signaling pathways involve in the ossification processes and regenerations of antlers. This article reviewed histological reports and regulatory mechanisms of hormones, cytokines and signal paths in this process to provide a reference for the study of ossification mechanisms and the improvement of antler production.