Abstract: Based on the scientific fact that climate resources and agricultural climate resources changed significantly and cloud and fog is the key meteorological factors that influences the quality of tea during tea growing period under the background of climate warming, the temporal and spatial variation of cloud and fog during different tea growing period (spring, summer, autumn) are analyzed by using the ground observation data from 81 meteorological stations from 1961 to 2010 in Guizhou Province. The results indicate that, the distribution of total cloud amount and percentage of the number of fog days in the study area showed a reducing trend from southeast to northwest during spring tea period, the total cloud amount was increased from the southeast to the northwest during summer tea period, while the total cloud amount during autumn tea period was decreasing from the northwest to southeast; The total cloud amount in summer tea period accounts for most in tea growing period, followed by spring tea and autumn tea, and the difference between the regions was generally smaller in these three period; The average of total cloud amount in spring, summer and autumn period all showed a decreasing trend form 1961 to 2010, the biggest decrease period was in autumn tea (-1.1% / 10a), followed by the summer tea (-0.5% / 10a) and spring tea (-0.17% / 10a).The largest percentage of the number of fog days was in autumn tea period, followed by spring and summer tea period, and the regional differences were larger in these three period. The percentage of the number of fog days showed an increasing trend for spring tea, summer tea, autumn tea, and winter tea, the climate trend rate was 5.1% /10a, 6.9%/10a and 7.2%/10a, respectively. Decrease of total cloud amount and the increase of the fog days during tea growing period in the study area will have a corresponding impact on variety screening, structural adjustment, as well as the tea yield and quality etc.