Abstract: The objective of this study is to solve the problems such as yield loss of no-till, environmental pollution of straw burning and unreasonable plantation structure. A field experiment with two types of tillage [conventional tillage (CT) and no- till (NT)] from 2013 to 2016 was conducted to evaluate the effects of continuous rotation and no-till of corn-soybean on soil nutrients and crop yield. The results indicated that soil total nitrogen, total phosphorus, total potassium, available nitrogen, available phosphorus, available potassium, organic matter at 0-7.5, 7.5-15, 15-22.5, and 22.5-30 cm depth of NT were higher than that of CT. Tillage had significant effect on soil nutrient except total potassium. Tillage had significant impacts on soil bulk density. Soil bulk density was higher at each soil layer under no-till than that of conventional tillage. The difference of soil bulk density between 15-22.5 cm and 22.5-30 cm under no-till was not significant, while the difference among different layers under conventional tillage was significant. Soybean yield under no- till increased by 16.37% and 25.33% compared with that of conventional tillage in 2013 and 2015, respectively. Corn yield under no-till increased by 0.88% and 9.50% compared with that of conventional tillage in 2014 and 2016, respectively. Soybean- corn rotation and no- till saved the cost of 640 yuan/hm2, and increased the income of 2220 yuan/hm2 compared with conventional tillage.