Abstract: In order to provide scientific basis of giving rational fertilization on rice NPK fertilizer. Different proportion experiment in nitrogen, phosphorus, and potassium fertilizers was used to study the reasonable mixed fertilizing rate of direct seeding rice. To Huanghuazhan as materials, the effects of main agronomic characters and biological characteristics were studied with different levels of NPK fertilizer. The results showed that, different level and rate of fertilizer influenced plant height, effective tillering and seeds per ear in some degree, then the performance in the yield differences was extremely obvious, the importance of the influence on output by three fertilizers were as followed by nitrogen, potassium and phosphorus. Fertilizer recommendations were nitrogen (N), phosphorus (P2O5), potassium (K2O) fertilizer were 224.85 kg/hm2, 31.30 kg/hm2 and 296.45 kg/hm2 respectively under the condition of this experiment.