Abstract: The trial was conducted to evaluate the possibility whether wheat could completely replace corn in the diet of laying hens. 180 laying hens were divided 2 experimented treatments, randomly, with 3 replicates and each of 30 layers. The trial adopted contrast design, treatment 1 fed with typical corn-soybean-meal diet, the other treatment fed with wheat-based diet. The results showed that the egg performance fed wheat-based diet was lower than treatment fed corn-soybean-meal diet : laying rate significantly decreased by 1.9%（p﹤0.05）, the rate of unusual shape egg and soft-shelled egg significantly increased by 0.09%（p﹤0.05）, feed to egg ratio significantly increased by 0.09（p﹤0.05）, feed intake significantly increased by 1.04%（p﹤0.05）, broken egg rate increased（p﹥0.05）, average egg weight decreased by 0.54% gram per egg（p﹥0.05）.energy utilization and protein apparent digestibility decreased without significant difference（p﹥0.05）. The feed cost in wheat-based diet reduced, but it was lower than treatment 1 in other indexes, and the egg cost of per kilogram increased by 0.01RMB.