Abstract: The results indicated that the Xianyou County is the serious area of farm-land mice. The Rattus losea is the key specie in the farm-land, And it is the Rattus flavipectus in houses. The rodents occurrence in peak period(during April to May, and from August to September) is the optimum control time. The chemical control is the main method of integrated control. In order to get the good control effect of the rodents ,it is very important of be acquaint with the dynamic of the rodents, selected the effective and safety pesticides ,the right method to spread the poisonous foods.