Welcome to Chinese Agricultural Science Bulletin,

Chinese Agricultural Science Bulletin ›› 2018, Vol. 34 ›› Issue (29): 98-103.doi: 10.11924/j.issn.1000-6850.casb17080068

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Growth Factors and Signaling Pathway Affect Hair Follicle Development: A Review

  

  • Received:2017-08-16 Revised:2018-09-21 Accepted:2017-12-21 Online:2018-10-15 Published:2018-10-15

Abstract: The development of hair follicle (HF) is cyclical, and its cyclogeny is regulated by many factors. The growth factors such as VEGF, HSP and EGF can affect the growth and development of hair follicles in a direct or indirect way. Some signaling pathways, such as Wnt and BMP/TGF beta also regulate hair follicle cycle and other life activities. We summarized the research progress on the regulators for HF development, including growth factors, hormones, active proteins and signal pathways. Finally, we put forward the potential research hotspot and application prospect of HF development.