Abstract: 【OBJECTIVE】The study on the interrelationship among the 4 factors of cultivating measurements (base density, N-fertilizer, P-fertilizer, K- fertilizer) and output of Brassica napus Qian You No.18 with choiceness 【METHOD】by applying the design of quadratic curvilinear regression combination in high altitude field(altitude950~1200m).The result showed that the yield mathematical model established by means of adjusting optimization together with analysis, defining the key divisors and synthetical agronomy measurements that Brassica napus Qian You No.18 with choiceness to growing that high production high efficiency optimizes, good means from a complete system in the interest of the improved variety in high altitude field. 【RESULTS】The results showed that the effect on yield is N-fertilizer>density> P-fertilizer>K-fertilizer. 【CONCLUSION】This model could make sure that the yield reach ≥2493.46kg/hm2,while the optimum comprehensive practices were used and the following indices of the primary density 136000~145000 plants /hm2, N-fertilizer 291.35~330.00 kg/hm2, P-fertilizer 92.28~102.27hm2, K-fertilizer 119.20~129.20kg/hm2.