Dynamic Observation on the T Lymphocyte Subgroups of Piglets Infected with Isospora suis

Abstract

Abstract: In order to reveal the dynamic changes of the T lymphocyte subgroups in piglets，nine six-day-old piglets were inoculated with Isospora suis sporulated occysts. CD3+, CD4+, CD8+ T cells were checked on before and post the day inoculation 1, 3, 6, 9, 11 (DPI), respectively. Results showed that the amounts of CD3+, CD4+ T cells increased on DPI 3 and then decreased, but the diversity was not significant (p>0.05); however, CD8＋ T cell raised on DPI 6 and reached peak value on DPI 9 (P<0.05). The ratio of CD4+/CD8+ began to descend on DPI 6, and came to the lowest point on DPI 11. Those indicated that the immunological functions of the piglets infected with I. suis were reinforced on DPI 3, however, which were suppressed after DPI 8 .

CLC Number:

S852.72+3

Wang Fang, Ning Changshen, Zhang Longxian, Jian Fuchun, Zhu Jingjing,Yao Lei, Zhang Min. Dynamic Observation on the T Lymphocyte Subgroups of Piglets Infected with Isospora suis[J]. Chinese Agricultural Science Bulletin, 2007, 23(9): 4-4.

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