Abstract: Botanical insecticide derived from plants, derived from the nature, is the true sense of pesticides without poison. Botanical insecticide can be degradation in the nature, and usually botanical insecticide will not pollute the environment and agricultural products. Basing on the performance of four kinds of Botanical insecticide on controlling to Pest Insects, such as Rice Borer, Yellow rice borer, Rice planthopper, Rice case worm etc, the author offers specifications for operation of non-pollution on rice growth stage systemically as follows: Problem-Oriented, at the right time, with the right methods, with the optimization amount, with the right frequency, in the right order, and with the right ratio.