Abstract:

Here, we examined the genetic diversity and phylogeographic structure of domestic goats by determining mitochondrial DNA （mtDNA）and microsatellite DNA. The genetic diversity of five goat breeds including Angora goat, Shandonglaiwu black goat, Hanshan white goat, Taihang goat and Wuzhumuqin goat was surveyed using twenty-five microsatellite loci，The UPGMA phylogenetic trees constructed with the Dcoa genetic distances between the five goat breeds supported a closer relationship between Hanshan White goat and Wuzhumuqin goat. Phylogenetic analyses revealed that there were two mtDNA lineages （A,C） identified in five goat breeds including Angora goat, Shandonglaiwu black goat, Lubei white goat, Taihang goat and Wuzhumuqin goat. Population genetic structure and population expansion were carried out. Comparison with mtDNA and microsatellite DNA revealed that microsatellite DNA is good marker for analyzing genetic diversity and genetic structure at the breed level , while mtDNA variation seems to be a poor assay in this aspect,but Mitochondrial DNA (mtDNA) has represented the most informative genomic element for untangling the origins of domestic animals