Abstract:

The fibrino(geno)lytic enzymes which wildly exist in many kinds of snake venoms can directly lysis fibrin(ogen). The fibrino(geno)lytic enzymes purified from snake venoms through the technology of protein separation display the potential value in the application of cardio-cerebrovascular disease. This article discusses the studies about physicochemical properties and enzymatic characterization of the venom fibrino(geno)lytic enzymes, as well as the related research in molecular biology and the development and application as thrombolytic agent.