Abstract: In order to provide adequate theoretical basis for reasonably nitrogen and silicon combined application, a field experiment was conducted to investigate the effects of nitrogen and silicon interaction on the nutrition and yield of rice. The results showed that, silicon application could significantly increase the solid grain number per panicle and 1000-grain weight; while nitrogen application could significantly increase the valid panicle number per plant, nitrogen and silicon combined application could increase the yield of rice. Added silicon fertilizer could significantly increase soil available silicon content, but added nitrogen fertilizer could significantly decrease soil available silicon content. Nitrogen application could increase nitrogen, phosphorus and potassium content of rice plant on each period, but silicon application had no significant effects. The results of the present study suggested that, the effects of nitrogen fertilizer in the presence of silicon fertilizer could be improved, the treatment (N 180 kg/hm2 and SiO2 30 kg/hm2) could obtain balanced nutrition and the highest yield of rice.