Abstract: Abstract : Through the internal detection and external temperature testing method, researching the dynamic changes in muskmelon fruit development and ABA influence fruit mature. The results indicated that: the IAA and ZR contents were higher in the early muskmelon development, GAs content gradually rised after the muskmelon slowly grow period, ABA content gradually increased after the mature of the muskmelon. After using the ABA-contained medium temperature, sucrose synthase was greatly improved, neutral invertase activities were significantly inhibited, sucrose of fruit discs content increased, glucose content droped. Comprehensive analysis thinks: The fruit of the early development of cell division and swelling are related with the IAA, ZR and Gas contents. ABA is probably one type of important hormones that start muskmelon mature, which adjusts to the fruit sucrose accumulation and promotes to mature fruit quality transformation through regulating sugar metabolism-related enzymes.