Abstract: In order to mitigate the occurrence and damage of cowpea whitefly, reduce chemical pesticide consumption, residue and environmental pollution, the methods of forecasting, randomized block design and statistical analysis were used in field efficacy trials, to study the control effect of cowpea anthracnose by using chemical pesticides dinotefuran, acetamiprid, pymetrozine, and bio-pesticide avermectin. The results showed that after applying 1.85% avermectin EC 375 g, 20% dinotefuran SP 600 g, 5% acetamiprid WP 600 g, and 25% pymetrozine WP 600 g (control pesticide) per hm² once every 5-8 days, and 3 times continuously under serious autumn occurrence of greenhouse whitefly, the control efficacy was 90.9%, 97.0%, 88.0%, 93.9% respectively on the 7^th day after the pesticides application; 97.4%, 92.1%, 84.2%, 89.4% respectively on the 14^th day after the pesticides application; and 95.6%, 86.7%, 82.2%, 84.5%, respectively on the 20^th day after the pesticides application. The control effects among avermectin, acetamiprid and pymetrozine were not significantly different, while the effects of avermectin and pymetrozine were significantly higher than that of acetamiprid on the 7^th day. The control effects among avermectin, dinotefuran and pymetrozine were not significantly different, while significantly higher than that of acetamiprid on the 14^th day. The control effect of avermectin was significantly higher than that of dinotefuran, acetamiprid and pymetrozine on the 20^th day. Meanwhile, the control effect of avermectin was slightly lower, higher and much higher than that of dinotefuran on the 7^th, 14^th, 20^th day respectively after the treatment. These results indicated that the four pesticides, especially bio-pesticide avermectin, were ideal pesticides, which could not only be used for controlling cowpea whitefly, but also realize modern, green, organic and ecological agricultural production.