Abstract: The cultivation mode of winter wheat with thousand catties by watering once in Hebei middle and south region indicates that during the whole growth period, the output of winter wheat is up to 7500 kg/hm2, because the technical measures of using water with soil moisture for seeding and water dual using in later period of corn were adopted under the circumstance of the rainfall capacity during the winter wheat growth period as close as the average rainfall capacity in recent 10 years. The author has found the theoretical basis of the cultivation mode of winter wheat with thousand catties by watering once through investigating a series of water saving cultivation tests in these cities of Shi Jiazhuang, Xingtai, Handan, Baoding, etc. which locate in the middle and south of Hebei province from 2011 to 2016: Firstly, the soil moisture is surplus after the harvest of the winter wheat in the mode of traditional watering and management; Secondly, the deep layer is available during the whole growth period of winter wheat in the mode of traditional watering and management; Thirdly, the total water capacity used in the cultivation mode of winter wheat with thousand catties by watering once is close to that used in high-field wheat in the mode of traditional watering and management. Based on these theoretical foundations, the author develops the cultivation mode of winter wheat with thousand catties by watering once with the main technical of water dual using, high output by sowing late, compacting after sowing、equal row cultivating, once watering, which were proved by two-year practical tests with the result of 8074.5 kg/hm2 output during 2014—2015 and 8130 kg/hm2 output during 2015—2016.