Abstract:

In order to systematacially discuss the effect of alfalfa polysaccharides on mice immunocyte proliferation and lay a foundation for the next deep research of alfalfa polysaccharides on the immune activity regulating, MMT assay were adopted to detect the effect of alfalfa polysaccharides on the proliferation of normal Balb/c mice bone marrow dendritic cells in vitro as well as the energy metabolism level of peritoneal macrophage. The results indicated that, alfalfa polysaccharides could stimulate the proliferation of mice bone marrow dendritic cells and the energy metabolism level improvement of peritoneal macrophage, which indicated that alfalfa polysaccharides could enhance antigen submission function of accessory cells. Consequently, alfalfa polysaccharides could improve immune competent cell function by enhancing antigen submission function of accessory cells.